Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100438 | 0.93 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL16100810 | 0.88 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL16121429 | 0.87 | BRAF (0.91) | BRAFRAF1 | |
| SCHEMBL16099653 | 0.85 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL16103183 | 0.83 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL20008526 | 0.82 | RAF1 (0.70) | BRAFRAF1 | |
| SCHEMBL20008242 | 0.80 | RAF1 (0.84) | BRAFRAF1 | |
| SCHEMBL16100708 | 0.80 | RAF1 (1.00) | BRAFRAF1 | |
| SCHEMBL16121512 | 0.77 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL25985380 | 0.77 | RAF1 (0.60) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |