Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956618 | 0.64 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL23654930 | 0.63 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8154014 | 0.61 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL16959282 | 0.60 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL22856978 | 0.60 | MEN1 (0.39) | MEN1KMT2AHPGDSMN1; SMN2TSHR | |
| SCHEMBL20009422 | 0.60 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL16119884 | 0.60 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL19346364 | 0.60 | MEN1 (0.44) | MEN1KMT2APOLBSMN1; SMN2TSHR | |
| SCHEMBL7734929 | 0.59 | TAAR1 (0.57) | MEN1KMT2AHPGDPOLB | |
| SCHEMBL13518614 | 0.59 | MEN1 (0.49) | MEN1KMT2AHPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |