Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.67 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20012396 | 0.93 | GPBAR1 (0.67) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL19705475 | 0.93 | GPBAR1 (0.67) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL20008829 | 0.88 | GPBAR1 (0.77) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL24212436 | 0.88 | GPBAR1 (0.77) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL22699678 | 0.86 | MAPT (0.83) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL4971166 | 0.86 | MAPT (0.83) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL20008826 | 0.86 | MAPT (0.73) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL20008825 | 0.85 | GPBAR1 (0.76) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL20012376 | 0.85 | GPBAR1 (0.76) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL20012515 | 0.85 | GPBAR1 (0.76) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086786-A1 | PREPARATION OF DEOXYCHOLIC ACID | CRYSTAL PHARMA S.A.U. (ES) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086786-A1 | PREPARATION OF DEOXYCHOLIC ACID | SLC10A1, DHCR7, NR1H4 | GPBAR1 11/4885NR1H4 3/4885SLC10A2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.