SCHEMBL20008833

SCHEMBL20008833

c1ccc(-c2cccc(-c3c4ccccc4c(-c4cccc(-c5ccncc5)c4)c4ccc(-c5ccccc5)cc34)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.52
MKNK1 Q9BUB5 1/20 0.51
PIK3CA P42336 1/20 0.50
IMPDH2 P12268 1/20 0.49
CHEK1 O14757 3/20 0.44
ALK Q9UM73 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
PRKCI P41743 1/20 0.42
KIF11 P52732 1/20 0.42
MAPK13 O15264 1/20 0.42
GCGR P47871 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42
CDK1 P06493 1/20 0.40
CDK4 P11802 1/20 0.40
CCNA2 P20248 1/20 0.40
CCND1 P24385 1/20 0.40
CDK2 P24941 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10030030 1.00 NOTUM (0.52) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL10030049 1.00 NOTUM (0.52) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL10030019 1.00 NOTUM (0.52) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL10030040 0.98 MKNK1 (0.50) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL10030035 0.97 NOTUM (0.52) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL17366611 0.95 NOTUM (0.54) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL17366606 0.95 NOTUM (0.54) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL10030046 0.93 NOTUM (0.52) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL15977849 0.93 NOTUM (0.52) NOTUMMKNK1PIK3CAIMPDH2CHEK1
SCHEMBL15977469 0.93 NOTUM (0.56) NOTUMMKNK1PIK3CAIMPDH2CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220223814-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-07-14 US disclosed
US-20200395547-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-17 US disclosed
US-20180090692-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed
US-20180090692-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090692-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, FOXM1, NOM1 NOTUM 949/4885MKNK1 964/4885PIK3CA 4522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.