Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19991596 | 0.92 | PIK3C2B (0.60) | PIK3R2PIK3C2B | |
| SCHEMBL19991566 | 0.90 | PIK3C2B (0.49) | PIK3R2PIK3C2B | |
| SCHEMBL20009348 | 0.88 | PIK3R2 (0.54) | PIK3R2PIK3C2B | |
| SCHEMBL19988850 | 0.87 | PIK3R2 (0.65) | PIK3R2PIK3C2B | |
| SCHEMBL19991627 | 0.87 | AKR1C3 (0.52) | PIK3R2PIK3C2B | |
| SCHEMBL19991619 | 0.84 | PIK3C2B (0.46) | PIK3R2PIK3C2B | |
| SCHEMBL19991565 | 0.84 | PIK3C2B (0.48) | PIK3R2PIK3C2B | |
| SCHEMBL19989174 | 0.84 | PIK3R2 (0.65) | PIK3R2 | |
| SCHEMBL19989121 | 0.83 | PIK3R2 (0.57) | PIK3R2PIK3C2B | |
| SCHEMBL19988955 | 0.83 | PIK3R2 (0.65) | PIK3R2PIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479770-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180086719-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20180086719-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2018-03-29 | — | — | US | disclosed |
| WO-2018057805-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086719-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PIK3CA, AKT3, PI4KA | PIK3R2 30/4885PIK3C2B 15/4885 |
| US-10479770-B2 | Phosphatidylinositol 3-kinase inhibitors | PIK3CA, AKT3, PI4KA | PIK3R2 30/4885PIK3C2B 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.