SCHEMBL20009858

SCHEMBL20009858

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4-c4ccc(-n5c6ccccc6c6c7ccccc7ccc65)cc4)cc3)c3ccc4ccccc4c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC4 P56524 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
PTGES O14684 2/20 0.30
ALOX5 P09917 1/20 0.30
PDE6D O43924 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24374020 0.96 KDM4E (0.36) KDM4EATML3MBTL1HDAC4PTGES
SCHEMBL24374285 0.96 KDM4E (0.36) KDM4EATML3MBTL1HDAC4PTGES
SCHEMBL20812713 0.94 KDM4E (0.37) KDM4EATML3MBTL1HDAC4ALDH1A1
SCHEMBL20009782 0.94 KDM4E (0.37) KDM4EATML3MBTL1HDAC4ALDH1A1
SCHEMBL26710277 0.93 KDM4E (0.35) KDM4EATML3MBTL1HDAC4PTGES
SCHEMBL24374120 0.93 KDM4E (0.35) KDM4EATML3MBTL1HDAC4PTGES
SCHEMBL24949059 0.93 KDM4E (0.36) KDM4EATML3MBTL1HDAC4ALDH1A1
SCHEMBL15138363 0.93 KDM4E (0.36) KDM4EATML3MBTL1HDAC4PTGES
SCHEMBL20009802 0.93 KDM4E (0.36) KDM4EATML3MBTL1HDAC4ALDH1A1
SCHEMBL24948580 0.93 KDM4E (0.31) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573824-B2 Compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2020-02-25 US disclosed
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-29 US disclosed
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090688-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, BMI1 KDM4E 390/4885ATM 2315/4885L3MBTL1 1563/4885
US-10573824-B2 Compound and organic electronic element comprising same OR10J3, ETV6, BMI1 KDM4E 390/4885ATM 2315/4885L3MBTL1 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.