⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21051910 | 0.77 | — | — | |
| SCHEMBL2658909 | 0.76 | — | — | |
| SCHEMBL7476337 | 0.74 | EGLN3 (0.48) | — | |
| SCHEMBL10911591 | 0.73 | — | — | |
| SCHEMBL4686079 | 0.72 | — | — | |
| SCHEMBL5657617 | 0.71 | CYP19A1 (0.48) | — | |
| SCHEMBL7470879 | 0.70 | EGLN3 (0.37) | — | |
| SCHEMBL20550616 | 0.70 | EGLN3 (0.37) | — | |
| SCHEMBL1696683 | 0.69 | EGLN3 (0.39) | — | |
| SCHEMBL1696686 | 0.69 | EGLN3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230347-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-15 | — | — | EP | claimed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | claimed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | claimed |
| EP-0061798-B1 | NOVEL ANTIMICROBIAL TRIAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-08-20 | — | — | EP | claimed |
| WO-2024071216-A1 | PYRAZOLE COMPOUND AND PEST CONTROL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | 三井化学クロップ＆ライフソリューション株式会社 | 2024-04-04 | — | — | WO | disclosed |
| WO-2023171783-A1 | PYRAZOLE COMPOUND, AND NOXIOUS ORGANISM CONTROL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2023-09-14 | — | — | WO | disclosed |
| EP-2763987-B1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE AS FUNGICIDALS | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-3153497-A2 | PESTICIDAL CARBOXAMIDES | Bayer Cropscience AG (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9023844-B2 | Heterocyclylpyri (mi) dinylpyrazole as fungicidals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-20140256677-A1 | HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-8017612-B2 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | JAPAN TOBACCO INC. (JP) | 2011-09-13 | — | — | US | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| CN-1052224-C | Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients | OTSUKA PHARMA CO LTD (JP) | 2000-05-10 | — | — | CN | disclosed |
| US-5760058-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |
| EP-0230347-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | disclosed |