Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R2 | O00459 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20011343 | 0.92 | PIK3R2 (0.56) | PIK3R2 | |
| SCHEMBL20000403 | 0.83 | PIK3R2 (0.78) | PIK3R2 | |
| SCHEMBL20000209 | 0.80 | PIK3R2 (0.79) | PIK3R2 | |
| SCHEMBL20000127 | 0.79 | PIK3R2 (0.79) | PIK3R2 | |
| SCHEMBL20000206 | 0.79 | PIK3R2 (0.76) | PIK3R2 | |
| SCHEMBL20000122 | 0.78 | PIK3R2 (0.77) | PIK3R2 | |
| SCHEMBL20000253 | 0.77 | PIK3R2 (0.78) | PIK3R2 | |
| SCHEMBL20000274 | 0.76 | PIK3R2 (0.78) | PIK3R2 | |
| SCHEMBL20000200 | 0.76 | PIK3R2 (0.78) | PIK3R2 | |
| SCHEMBL20000241 | 0.75 | PIK3R2 (0.80) | PIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057808-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2018-03-29 | — | — | WO | disclosed |