Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 3/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22199576 | 1.00 | KMT2A (0.62) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL22199575 | 1.00 | KMT2A (0.62) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL20013329 | 1.00 | KMT2A (0.62) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL17751714 | 0.95 | KMT2A (0.56) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL17751719 | 0.95 | KMT2A (0.56) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL17751724 | 0.95 | KMT2A (0.56) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL13254138 | 0.95 | KMT2A (0.56) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL17751716 | 0.95 | KMT2A (0.56) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL17751718 | 0.95 | KMT2A (0.56) | KMT2AFABP7FABP5TLR2TLR1 | |
| SCHEMBL17751637 | 0.95 | KMT2A (0.56) | KMT2AFABP7FABP5TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358988-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200216498-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-07-09 | — | — | US | disclosed |
| US-10633419-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180086793-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633419-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | KMT2A 3513/4885FABP7 1288/4885FABP5 638/4885 |
| US-11358988-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | KMT2A 3513/4885FABP7 1288/4885FABP5 638/4885 |
| US-20180086793-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | KMT2A 3513/4885FABP7 1288/4885FABP5 638/4885 |
| US-20200216498-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | KMT2A 3513/4885FABP7 1288/4885FABP5 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.