SCHEMBL200157

SCHEMBL200157

CCCC[C](Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL834013 0.90
SCHEMBL3853521 0.87 TSHR (0.62)
SCHEMBL338424 0.87 TSHR (0.62)
SCHEMBL958616 0.87
SCHEMBL10643364 0.87 TSHR (0.62)
SCHEMBL11717241 0.87 TSHR (0.62)
SCHEMBL831615 0.77
Hexane SCHEMBL11409372 0.76
Pentane SCHEMBL11410718 0.76
SCHEMBL6156290 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057559-B Preparation method of diaryl ketone 中南民族大学 2023-10-03 CN claimed
CN-104968710-A Mobile electronic device made of low-chlorine aromatic polysulphone SOLVAY SPECIALTY POLYMERS USA 2015-10-07 CN claimed
CN-115175967-B Ionic liquids for stabilizing viscosity of silicate-based coatings 巴斯夫欧洲公司 2024-06-14 CN disclosed
WO-2024053650-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST DIACYLGLYCEROL KINASE α AND/OR ζ, AND PHARMACEUTICAL USE THEREOF 小野薬品工業株式会社 2024-03-14 WO disclosed
US-11851388-B2 Compound of 1-acetyl-6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline FMC AGRO SINGAPORE PTE. LTD. (SG) 2023-12-26 US disclosed
CN-114057559-B Preparation method of diaryl ketone 中南民族大学 2023-10-03 CN disclosed
CN-114057559-B Preparation method of diaryl ketone 中南民族大学 2023-10-03 CN disclosed
US-20230042328-A1 IONIC LIQUID FOR STABILIZING VISCOSITY OF SILICATE-BASED COATINGS BASF SE (DE) 2023-02-09 US disclosed
CN-115175967-A Ionic liquids for stabilizing viscosity of silicate-based coatings 巴斯夫欧洲公司 2022-10-11 CN disclosed
CN-109071439-B Process for preparing 4-aminoindane derivatives and related aminoindane amides I-F产品协作基金会 2022-07-15 CN disclosed
CN-114728884-A Process for the preparation of (R) -4-aminoindanes and corresponding amides FMC农产品国际有限公司 2022-07-08 CN disclosed
US-20050020667-A1 Compounds and therapies for the prevention of vascular and non-vascular pathologies PONIARD PHARMACEUTICALS, INC. 2005-01-27 US disclosed
US-6734208-B2 ADJUSTMENT TRANSFORMING GROWTH FACTOR CONCENTRATION; ANTIINFLAMMATORY AGENTS NEORX CORPORATION 2004-05-11 US disclosed
US-20030064970-A1 Compounds and therapies for the prevention of vascular and non-vascular pathologies NEORX CORPORATION 2003-04-03 US disclosed
US-6410587-B1 FIBROSIS; ALZHEIMER'S DISEASE; ANTIARTHRITIC AGENTS NEORX CORPORATION 2002-06-25 US disclosed
US-6117911-A ADMINISTRATION OF AT LEAST ONE THERAPEUTIC AGENT THAT ELEVATES THE LEVEL OF TGF-BETA IN SAID MAMMAL. NEORX CORPORATION (US) 2000-09-12 US disclosed
CN-1253965-A Aromatic method for stabilizing halopolymer MORTON INT INC (US) 2000-05-24 CN disclosed
WO-1998046588-A2 COMPOUNDS AND THERAPIES FOR THE PREVENTION OF VASCULAR AND NON-VASCULAR PATHOLOGIES NEORX CORPORATION (US) 1998-10-22 WO disclosed
CN-1144227-A Process for preparation of aromatic sulfur-containing polymers HOECHST AG (DE) 1997-03-05 CN disclosed
CN-1120045-A New cephalosporins containing in position 7 a substituted benzyloxyimino radical, their preparation process, their use as medicaments ROUSSEL UCLAF (FR) 1996-04-10 CN disclosed