Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.57 |
| ▸ | SHBG | P04278 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25304277 | 0.82 | ESR1 (0.67) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL20010697 | 0.76 | ESR1 (0.61) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL20015657 | 0.76 | ESR1 (0.61) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL24399389 | 0.76 | ESR1 (0.61) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| Estradiol SCHEMBL28211603 | 0.76 | ESR1 (0.95) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| Estradiol SCHEMBL1741766 | 0.75 | ESR1 (0.89) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL8776086 | 0.75 | ESR1 (0.54) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| Estradiol SCHEMBL9058664 | 0.74 | ESR1 (0.97) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| Alfatradiol SCHEMBL28241801 | 0.74 | ESR1 (0.87) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 | |
| Estradiol SCHEMBL21899742 | 0.74 | ESR1 (0.85) | ESR1ESR2LMNAHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10400006-B2 | Estrogen receptor modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180086787-A1 | ESTROGEN RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10400006-B2 | Estrogen receptor modulators | ESR2, ESRRA, ESRRB | ESR1 5/4885ESR2 1/4885LMNA 1848/4885 |
| US-20180086787-A1 | ESTROGEN RECEPTOR MODULATORS | ESR2, ESRRA, ESRRB | ESR1 5/4885ESR2 1/4885LMNA 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.