SCHEMBL20017843

SCHEMBL20017843

C#C[C@H]1CNCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25658774 1.00
SCHEMBL3263836 1.00
Hydrochloric Acid SCHEMBL28765497 0.98
Hydrochloric Acid SCHEMBL28765499 0.98
Formaldehyde SCHEMBL29221302 0.94
Trifluoroacetic Acid SCHEMBL28864656 0.82 SSTR4 (0.31)
SCHEMBL2444590 0.78
Hydrochloric Acid SCHEMBL29753521 0.77
SCHEMBL5265334 0.76
SCHEMBL7319 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503468-B2 Heterocyclic compound, intermediate, preparation method therefor and application thereof WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2025-12-23 US disclosed
CN-119490467-A Heterocyclyl compound containing dibromovinyl group and preparation method and application thereof 武汉朗来科技发展有限公司 2025-02-21 CN disclosed
CN-119039290-A P2X3 modulators 葛兰素史密斯克莱知识产权(第3号)有限公司 2024-11-29 CN disclosed
CN-113272301-B Heterocyclic compound, intermediate, preparation method and application thereof 武汉朗来科技发展有限公司 2024-04-26 CN disclosed
US-20240034729-A9 HETEROCYCLIC COMPOUND, INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2024-02-01 US disclosed
US-20230312557-A1 P2X3 MODULATORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) 2023-10-05 US disclosed
CN-115043836-B P2X3 receptor selective modulator of imidazopyridine derivative and pharmaceutical application thereof 苏州璞正医药有限公司 2023-07-18 CN disclosed
US-20230068538-A1 HETEROCYCLIC COMPOUND, INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF WUHAN LL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD (CN) 2023-03-02 US disclosed
WO-2023020156-A1 P2X3 RECEPTOR-SELECTIVE MODULATOR OF IMIDAZOPYRIDINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF 苏州璞正医药有限公司 2023-02-23 WO disclosed
EP-4103564-A1 P2X3 MODULATORS Bellus Health Cough Inc. (CA) 2022-12-21 EP disclosed
CN-115413279-A P2X3 modulators 贝卢斯医疗咳嗽病公司 2022-11-29 CN disclosed
CN-115043836-A P2X3 receptor selective regulator of imidazopyridine derivative and pharmaceutical application thereof 苏州璞正医药有限公司 2022-09-13 CN disclosed
EP-3889154-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Wuhan LL Science And Technology Development Co., Ltd. (CN) 2021-10-06 EP disclosed
EP-3889154-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Wuhan LL Science And Technology Development Co., Ltd. (CN) 2021-10-06 EP disclosed
EP-3381917-B1 IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF BELLUS HEALTH COUGH INC (CA) 2021-09-08 EP disclosed
CN-113272301-A Heterocyclic compound, intermediate, preparation method and application thereof 武汉朗来科技发展有限公司 2021-08-17 CN disclosed
CN-111377917-A Heterocyclic compound, intermediate, preparation method and application thereof 武汉朗来科技发展有限公司 2020-07-07 CN disclosed
WO-2020135771-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2020-07-02 WO disclosed
WO-2020135771-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2020-07-02 WO disclosed
EP-2951177-B1 IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF NEOMED INST (CA) 2018-04-04 EP disclosed