Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 20/20 | 0.80 |
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15471971 | 0.89 | PDE2A (0.77) | PDE2APDE10A | |
| SCHEMBL15471803 | 0.89 | PDE2A (1.00) | PDE2APDE10A | |
| SCHEMBL15471976 | 0.89 | PDE2A (0.81) | PDE2APDE10A | |
| SCHEMBL20018165 | 0.87 | PDE2A (0.80) | PDE2APDE10A | |
| SCHEMBL15471864 | 0.86 | PDE2A (1.00) | PDE2APDE10A | |
| SCHEMBL15471872 | 0.84 | PDE2A (1.00) | PDE2APDE10A | |
| SCHEMBL15471889 | 0.84 | PDE2A (1.00) | PDE2APDE10A | |
| SCHEMBL15471868 | 0.83 | PDE2A (1.00) | PDE2APDE10A | |
| SCHEMBL15472974 | 0.82 | PDE2A (0.83) | PDE2APDE10A | |
| SCHEMBL15471851 | 0.82 | PDE2A (1.00) | PDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882749-B1 | 4-METHYL-2,3,5,9,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALENES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-04 | — | — | EP | disclosed |