Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405084 | 0.86 | SCN10A (0.41) | PARP1CDC7CCNE1CDK2ROCK1 | |
| SCHEMBL16405115 | 0.86 | SCN10A (0.41) | PARP1CDC7CCNE1CDK2ROCK1 | |
| SCHEMBL1494644 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL12294943 | 0.72 | KDM4E (0.39) | — | |
| SCHEMBL5950039 | 0.63 | CDC7 (0.44) | PARP1CDC7ROCK1DBF4 | |
| SCHEMBL17464840 | 0.60 | CDC7 (0.31) | PARP1CDC7CCNE1CDK2ROCK1 | |
| SCHEMBL69879 | 0.58 | — | — | |
| SCHEMBL18815650 | 0.55 | SCN10A (0.44) | PARP1CDC7CCNE1CDK2ROCK1 | |
| SCHEMBL18815648 | 0.55 | SCN10A (0.44) | PARP1CDC7CCNE1CDK2ROCK1 | |
| SCHEMBL18870909 | 0.55 | SCN10A (0.44) | PARP1CDC7CCNE1CDK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621279-B1 | FUSED TETRACYCLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2018-04-04 | — | — | EP | disclosed |