Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15787610 | 0.85 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3DAODHODH | |
| SCHEMBL15787465 | 0.83 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3DAODHODH | |
| SCHEMBL15787453 | 0.83 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3DAODHODH | |
| SCHEMBL15787436 | 0.81 | BACE1 (0.47) | STAT3ADRB2MMP13 | |
| SCHEMBL15787607 | 0.81 | BACE1 (0.47) | STAT3ADRB2MMP13 | |
| SCHEMBL15787606 | 0.81 | BACE1 (0.47) | STAT3ADRB2MMP13 | |
| SCHEMBL15784914 | 0.80 | STAT3 (0.37) | SLC6A2SLC6A4SLC6A3STAT3ADRB2 | |
| SCHEMBL15784615 | 0.80 | STAT3 (0.37) | SLC6A2SLC6A4SLC6A3STAT3ADRB2 | |
| SCHEMBL15784610 | 0.80 | STAT3 (0.37) | SLC6A2SLC6A4SLC6A3STAT3ADRB2 | |
| SCHEMBL2690913 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DAODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697229-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |