Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 20/20 | 0.80 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988409 | 0.89 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL9987734 | 0.75 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL15159018 | 0.75 | SLC22A12 (0.77) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL15159016 | 0.74 | SLC22A12 (0.67) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL15159020 | 0.72 | SLC22A12 (0.74) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL12071486 | 0.72 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL9987801 | 0.72 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL21727907 | 0.71 | SLC22A12 (0.59) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL12070811 | 0.69 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL9987694 | 0.68 | SLC22A12 (0.78) | SLC22A12SLC22A6SLC22A11ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975025-B1 | THIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |