Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24653597 | 0.81 | HPGD (0.53) | MAPTKDM4ELMNAHPGDMAPK1 | |
| SCHEMBL20686437 | 0.80 | GAA (0.67) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL20686393 | 0.79 | GAA (0.44) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL20686419 | 0.77 | GRIN2D (0.45) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL24766141 | 0.77 | KMT2A (0.55) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL21861415 | 0.76 | DHODH (0.54) | KMT2AKDM4EHPGDMEN1 | |
| SCHEMBL19176502 | 0.75 | MAPT (0.53) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL13451595 | 0.74 | GAA (0.53) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL19954734 | 0.73 | CYP1A2 (0.42) | GAAMAPTKMT2AKDM4ETDP1 | |
| SCHEMBL24004505 | 0.70 | RXFP1 (0.36) | GAAMAPTKMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649080-B1 | INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KK (JP) | 2018-04-04 | — | — | EP | disclosed |