Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949365 | 0.88 | HRH3 (0.59) | MAOBHRH3NPC1RAB9ABCHE | |
| SCHEMBL18388576 | 0.82 | HPGD (0.56) | HPGDNPC1RAB9ATP53TSHR | |
| SCHEMBL11701844 | 0.82 | HRH2 (0.58) | MAOBHRH3NPC1RAB9AHRH2 | |
| SCHEMBL9431699 | 0.82 | TP53 (0.55) | HPGDMAOBHRH3NPC1RAB9A | |
| SCHEMBL5215438 | 0.81 | HRH3 (0.63) | MAOBHRH3NPC1RAB9ABCHE | |
| SCHEMBL9156027 | 0.81 | NPC1 (0.60) | HPGDMAOBHRH3NPC1RAB9A | |
| SCHEMBL12420657 | 0.81 | TP53 (0.57) | HRH2HRH1TP53TSHR | |
| SCHEMBL1335721 | 0.80 | HRH3 (0.62) | MAOBHRH3NPC1RAB9ABCHE | |
| SCHEMBL14438609 | 0.80 | HPGD (0.53) | HPGDNPC1TP53TSHR | |
| SCHEMBL17949768 | 0.80 | HRH3 (0.61) | MAOBHRH3NPC1RAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3219776-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2019-07-24 | — | — | EP | disclosed |
| EP-3301141-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-04-04 | — | — | EP | disclosed |