Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021512 | 1.00 | CNR2 (0.43) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20021514 | 0.99 | CNR2 (0.44) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20022376 | 0.97 | CNR2 (0.41) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20021519 | 0.88 | CNR2 (0.53) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20021511 | 0.88 | CNR2 (0.53) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20021506 | 0.88 | CNR2 (0.53) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20021527 | 0.88 | CNR2 (0.53) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20021528 | 0.88 | CNR2 (0.53) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12379833 | 0.86 | PSEN1 (0.52) | CNR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20022299 | 0.85 | CNR2 (0.50) | CNR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094192-A1 | POLYMER NETWORKS | UNIVERSITY OF HULL (GB) | 2018-04-05 | — | — | US | disclosed |