Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| .Beta.-Hydroxyisovaleric Acid SCHEMBL95499 | 0.91 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL30764083 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL29991820 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL28000704 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL10277346 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL2340215 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL31058606 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL30764122 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL723161 | 0.88 | — | — | |
| .Beta.-Hydroxyisovaleric Acid SCHEMBL5159910 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110217759-A1 | STRAINS OF BACTERIA AND PHARMACEUTICAL COMPOSITION CONTAINING ONE OR MORE OF SUCH STRAINS AND USE OF SAME FOR PREVENTING AND TREATING DISEASES ASSOCIATED WITH OR CAUSED BY ALTERED METABOLISM OF BILE ACIDS | VSL PHARMACEUTICALS, INC. (IT) | 2011-09-08 | — | — | US | disclosed |
| US-7959911-B2 | Enzymatic polypeptide for use in the treatment of defects in ble metabolism | VSL PHARMACEUTICALS INC. (US) | 2011-06-14 | — | — | US | disclosed |
| EP-1721527-B1 | Lipase and use of same for improving doughs and baked products | DANISCO (DK) | 2010-06-09 | — | — | EP | disclosed |
| US-RE41276-E1 | STRAINS OF BACTERIA AND PHARMACEUTICAL COMPOSITION CONTAINING ONE OR MORE OF SUCH STRAINS AND USE OF SAME FOR PREVENTING AND TREATING DISEASES ASSOCIATED WITH OR CAUSED BY ALTERED METABOLISM OF BILE ACIDS | VSL PHARMACEUTICALS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| EP-0977869-B2 | LIPASE AND USE OF SAME FOR IMPROVING DOUGHS AND BAKED PRODUCTS | DANISCO (DK) | 2008-11-12 | — | — | EP | disclosed |
| US-7371423-B2 | Method for preparing flour doughs and products made from such doughs using lipase | DANISCO, A/S (DK) | 2008-05-13 | — | — | US | disclosed |
| EP-1721527-A2 | Lipase and use of same for improving doughs and baked products | DANISCO A/S (DK) | 2006-11-15 | — | — | EP | disclosed |
| EP-1679373-A2 | Lipase and use of same for improving doughs and baked products | DANISCO A/S (DK) | 2006-07-12 | — | — | EP | disclosed |
| EP-1433852-B1 | Use of lipase for improving doughs and baked products | DANISCO (DK) | 2006-06-28 | — | — | EP | disclosed |
| EP-1466980-B1 | Lipase and use of same for improving doughs and baked products | DANISCO (DK) | 2006-06-28 | — | — | EP | disclosed |
| US-20040071853-A1 | For improving rheological properties of a flour dough and the quality of bread, alimentary paste products, noodles and cakes | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2004-04-15 | — | — | US | disclosed |
| EP-0795604-B1 | Strains of bacteria with altered metabolism of bile acids and their use | DE SIMONE CLAUDIO (IT) | 2003-08-06 | — | — | EP | disclosed |
| US-20030108641-A1 | Improving rheological properties and quality of bread, alimentary paste products, noodles; strength and stability | DANISCO A/S (DK) | 2003-06-12 | — | — | US | disclosed |
| US-20030082791-A1 | Strains of bacteria and pharmaceutical composition containing one or more of such strains and use of same for preventing and treating diseases associated with or caused by altered metabolism of bile acids | VSL PHARMACEUTICALS INC. | 2003-05-01 | — | — | US | disclosed |
| EP-0973399-B1 | IMPROVED METHOD FOR PREPARING FLOUR DOUGHS AND PRODUCTS MADE FROM SUCH DOUGHS USING GLYCEROL OXIDASE | DANISCO (DK) | 2002-07-17 | — | — | EP | disclosed |
| US-6406723-B1 | ADJUSTING RHEOLOGY PROPERTIES | DANISCO A/S (DK) | 2002-06-18 | — | — | US | disclosed |
| EP-1193314-A1 | Lipase and use of same for improving doughs and baked products | DANISCO A/S (DK) | 2002-04-03 | — | — | EP | disclosed |
| US-20010012629-A1 | Strains of bacteria and pharmaceutical composition containing one or more of such strains and use of same for preventing and treating diseases associated with or caused by altered metabolism of bile acids | CLAUDIO DESIMONE (IT) | 2001-08-09 | — | — | US | disclosed |
| US-6225104-B1 | Strains of bacteria and pharmaceutical composition containing one or more of such strains and use of same for preventing and treating diseases associated with or caused by altered metabolism of bile acids | CAVALIERE VESELY RENATA MARIA (IT) | 2001-05-01 | — | — | US | disclosed |
| EP-0795604-A2 | Strains of bacteria with altered metabolism of bile acids and their use | Cavaliere Vesely, Renata Maria Anna (IT) | 1997-09-17 | — | — | EP | disclosed |