Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152552 | 0.97 | CTNNB1 (0.54) | CTNNB1BCL9 | |
| SCHEMBL18165188 | 0.97 | CTNNB1 (0.54) | CTNNB1BCL9 | |
| SCHEMBL18152317 | 0.88 | BCL9 (0.65) | CTNNB1BCL9 | |
| SCHEMBL18165168 | 0.88 | BCL9 (0.57) | CTNNB1BCL9 | |
| SCHEMBL18152550 | 0.88 | CTNNB1 (0.46) | CTNNB1BCL9 | |
| SCHEMBL18152555 | 0.88 | CTNNB1 (0.46) | CTNNB1BCL9 | |
| SCHEMBL18152553 | 0.88 | CTNNB1 (0.46) | CTNNB1BCL9 | |
| SCHEMBL18152315 | 0.87 | BCL9 (0.64) | CTNNB1BCL9 | |
| SCHEMBL18165192 | 0.86 | CTNNB1 (0.53) | CTNNB1BCL9 | |
| SCHEMBL18152349 | 0.86 | BCL9 (0.66) | CTNNB1BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180092866-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092866-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | BCL9, BCL9L, BCL3 | CTNNB1 4/4885BCL9 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.