⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262654 | 1.00 | ACE (0.44) | — | |
| SCHEMBL7411 | 1.00 | — | — | |
| SCHEMBL8089 | 1.00 | — | — | |
| Methane SCHEMBL14937660 | 0.98 | ACE (0.43) | — | |
| Hydrochloric Acid SCHEMBL11775905 | 0.98 | ACE (0.43) | — | |
| SCHEMBL29507635 | 0.98 | ACE (0.43) | — | |
| Water SCHEMBL28773339 | 0.98 | ACE (0.43) | — | |
| SCHEMBL9312770 | 0.98 | ACE (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL20920825 | 0.98 | ACE (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL28912295 | 0.98 | ACE (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098072-A1 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS | ENDEVICA BIO INC (US) | 2026-04-09 | — | — | US | claimed |
| EP-4665374-A1 | METHODS OF PREVENTING AND/OR TREATING SIDE EFFECTS ASSOCIATED WITH ANTI-CANCER AGENTS USING NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS WITH ANTI-GDF-15 ANTIBODIES | Endevica Bio, Inc. (US) | 2025-12-24 | — | — | EP | claimed |
| WO-2025245279-A1 | NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONISTS AND USE THEREFORE IN TREATMENT OF ADDICTION AND/OR PAIN | ENDEVICA BIO, INC. (US) | 2025-11-27 | — | — | WO | claimed |
| EP-4629981-A2 | SMALL MOLECULE DEGRADERS OF C-SRC KINASE | The Regents Of The University Of Michigan (US) | 2025-10-15 | — | — | EP | claimed |
| EP-4605407-A2 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS | Endevica Bio, Inc. (US) | 2025-08-27 | — | — | EP | claimed |
| EP-4590347-A1 | NOVEL MINIGASTRIN-DERIVED CHOLECYSTOKININ 2 RECEPTOR BINDING MOLECULES FOR IMAGING AND TARGETED RADIOTHERAPY | Technische Universität München (DE) | 2025-07-30 | — | — | EP | claimed |
| WO-2025123059-A1 | NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS AND USES THEREOF FOR TREATING SUBSTANCE USE DISORDERS | ENDEVICA BIO, INC. (US) | 2025-06-12 | — | — | WO | claimed |
| CN-119907695-A | Novel small gastrin-derived cholecystokinin 2 receptor binding molecules for imaging and targeted radiotherapy | 慕尼黑工业大学 | 2025-04-29 | — | — | CN | claimed |
| WO-2024177909-A1 | METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT IN SUBJECTS HAVING A FIBROTIC DISEASE USING NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS | ENDEVICA BIO, INC. (US) | 2024-08-29 | — | — | WO | claimed |
| WO-2024177907-A2 | METHODS OF TREATING CANCER AND/OR CHEMOTHERAPY RELATED CONDITIONS USING NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS | ENDEVICA BIO, INC. (US) | 2024-08-29 | — | — | WO | claimed |
| US-5352769-A | Genetic engineering | ELI LILLY AND COMPANY (US) | 1994-10-04 | — | — | US | claimed |
| EP-0383472-A2 | Insulin analogs | ELI LILLY AND COMPANY (US) | 1990-08-22 | — | — | EP | claimed |
| EP-0176070-B1 | PHARMACOLOGICALLY ACTIVE PEPTIDES | Brantl, Victor, Dr. med., Dipl.-Chem. (DE) | 1989-04-19 | — | — | EP | claimed |
| US-4657892-A | ANALGESICS, HYPOTENSIVE AGENTS | BRANTL VICTOR (DE) | 1987-04-14 | — | — | US | claimed |
| EP-0137339-B1 | PHARMACOLOGICALLY ACTIVE PEPTIDES | Brantl, Victor, Dr. med., Dipl.-Chem. (DE) | 1987-03-18 | — | — | EP | claimed |
| EP-0197059-A1 | PHARMACOLOGICALLY ACTIVE PEPTIDE | Brantl, Victor, Dr. med., Dipl.-Chem. (DE) | 1986-10-15 | — | — | EP | claimed |
| WO-1986002079-A1 | PHARMACOLOGICALLY ACTIVE PEPTIDE | BRANTL VICTOR (DE) | 1986-04-10 | — | — | WO | claimed |
| EP-0176070-A1 | Pharmacologically active peptides | Brantl, Victor, Dr. med., Dipl.-Chem. (DE) | 1986-04-02 | — | — | EP | claimed |
| EP-0137339-A1 | Pharmacologically active peptides | Brantl, Victor, Dr. med., Dipl.-Chem. (DE) | 1985-04-17 | — | — | EP | claimed |
| WO-1985001292-A1 | PHARMACOLOGICALLY ACTIVE PEPTIDES | BRANTL VICTOR | 1985-03-28 | — | — | WO | claimed |