SCHEMBL20024310

SCHEMBL20024310

CCCCC(CC)Cn1c(O)c(/N=N/c2ccc(C(=O)N(CCCC)CCCC)cc2)c(C)c(C#N)c1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.42
TDP1 Q9NUW8 1/20 0.42
KMT2A Q03164 7/20 0.41
MEN1 O00255 6/20 0.41
ALDH1A1 P00352 4/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
USP2 O75604 1/20 0.40
RAB9A P51151 1/20 0.40
MCL1 Q07820 1/20 0.40
MAP4K1 Q92918 1/20 0.37
KDM4E B2RXH2 2/20 0.36
MITF O75030 1/20 0.36
THRB P10828 1/20 0.36
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20024311 0.94 MAPT (0.43) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL16382617 0.93 MAPT (0.42) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL20024330 0.88 MAPT (0.47) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL17944315 0.87 KMT2A (0.46) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL15243135 0.87 MAPT (0.43) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL20024318 0.87 MAP4K1 (0.45) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL17368972 0.87 MAPT (0.37) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL23489740 0.87 KMT2A (0.48) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL18269327 0.87 KMT2A (0.45) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL18269324 0.87 KMT2A (0.45) MAPTTDP1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801703-B2 Heat sensitive transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2023-10-31 US disclosed
US-11801703-B2 Heat sensitive transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2023-10-31 US disclosed
US-20200407572-A1 HEAT SENSITIVE TRANSFER RECORDING SHEET CANON KABUSHIKI KAISHA (JP) 2020-12-31 US disclosed
US-20180095374-A1 MIXTURE, TONER, AND DISPERSION CANON KABUSHIKI KAISHA (JP) 2018-04-05 US disclosed
US-20180095374-A1 MIXTURE, TONER, AND DISPERSION CANON KABUSHIKI KAISHA (JP) 2018-04-05 US disclosed