SCHEMBL20024323

SCHEMBL20024323

CCCCn1c(O)c(/N=N/c2ccc(C(=O)NCC)cc2)c(C)c(C#N)c1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.50
MEN1 O00255 10/20 0.50
MAPT P10636 8/20 0.50
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 3/20 0.48
PKM P14618 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.46
USP2 O75604 1/20 0.46
RAB9A P51151 1/20 0.46
MCL1 Q07820 1/20 0.46
KDM4E B2RXH2 4/20 0.42
MITF O75030 1/20 0.42
THRB P10828 1/20 0.42
ALPL P05186 1/20 0.40
ALPG P10696 1/20 0.40
SAE1 Q9UBE0 4/20 0.38
UBA2 Q9UBT2 4/20 0.38
CNR2 P34972 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18269314 0.92 KMT2A (0.50) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL20024320 0.91 MAPT (0.47) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL20024325 0.90 MAPT (0.43) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL9491548 0.90 KMT2A (0.54) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL18269320 0.89 MAPT (0.55) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL18269312 0.88 MAP4K1 (0.52) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL18269315 0.87 KMT2A (0.49) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL20024337 0.87 MAPT (0.62) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL20024298 0.87 MAPT (0.48) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL9816832 0.86 KMT2A (0.66) KMT2AMEN1MAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801703-B2 Heat sensitive transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2023-10-31 US disclosed
US-11801703-B2 Heat sensitive transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2023-10-31 US disclosed
US-20200407572-A1 HEAT SENSITIVE TRANSFER RECORDING SHEET CANON KABUSHIKI KAISHA (JP) 2020-12-31 US disclosed
US-20180095374-A1 MIXTURE, TONER, AND DISPERSION CANON KABUSHIKI KAISHA (JP) 2018-04-05 US disclosed
US-20180095374-A1 MIXTURE, TONER, AND DISPERSION CANON KABUSHIKI KAISHA (JP) 2018-04-05 US disclosed