Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 20/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133607 | 1.00 | CAPN1 (0.56) | CAPN1CTSS | |
| SCHEMBL23268990 | 0.86 | CAPN1 (0.59) | CAPN1CTSS | |
| SCHEMBL20028632 | 0.86 | CAPN1 (0.59) | CAPN1CTSS | |
| SCHEMBL20027563 | 0.85 | CAPN1 (0.56) | CAPN1CTSS | |
| SCHEMBL20027471 | 0.84 | CAPN1 (0.56) | CAPN1CTSS | |
| SCHEMBL20028622 | 0.83 | CAPN1 (0.58) | CAPN1CTSS | |
| SCHEMBL20028455 | 0.83 | CAPN1 (0.58) | CAPN1CTSS | |
| SCHEMBL21854023 | 0.82 | CAPN1 (0.54) | CAPN1CTSS | |
| SCHEMBL21854058 | 0.82 | CAPN1 (0.52) | CAPN1CTSS | |
| SCHEMBL21854045 | 0.82 | CAPN1 (0.54) | CAPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |