Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425631 | 1.00 | PRKDC (0.63) | PRKDC | |
| SCHEMBL15006872 | 0.94 | PRKDC (0.72) | PRKDC | |
| SCHEMBL3418762 | 0.89 | PRKDC (0.53) | PRKDC | |
| SCHEMBL15006674 | 0.86 | PRKDC (0.78) | PRKDC | |
| SCHEMBL16215874 | 0.85 | PRKDC (0.54) | PRKDC | |
| SCHEMBL15006756 | 0.85 | PRKDC (0.86) | PRKDC | |
| SCHEMBL15006749 | 0.85 | PRKDC (0.86) | PRKDC | |
| SCHEMBL249922 | 0.85 | PRKDC (0.86) | PRKDC | |
| SCHEMBL15006697 | 0.83 | PRKDC (0.75) | PRKDC | |
| SCHEMBL249277 | 0.82 | PRKDC (0.64) | PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064092-A1 | METHOD FOR TREATING CANCER USING A COMBINATION OF DNA-DAMAGING AGENTS AND DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-04-05 | — | — | WO | disclosed |