Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 19/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 3/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19899990 | 0.92 | NR1H4 (0.49) | NR1H4RETFABP1FABP4 | |
| SCHEMBL19899995 | 0.91 | NR1H4 (0.50) | NR1H4RET | |
| SCHEMBL19899994 | 0.91 | NR1H4 (0.40) | NR1H4RETFABP1FABP4 | |
| SCHEMBL19900884 | 0.91 | NR1H4 (0.51) | NR1H4FABP1FABP4 | |
| SCHEMBL30437269 | 0.91 | NR1H4 (0.40) | NR1H4RETFABP1FABP4 | |
| SCHEMBL2084116 | 0.89 | NR1H4 (0.41) | NR1H4 | |
| SCHEMBL29385188 | 0.88 | NR1H4 (0.52) | NR1H4RETFABP1 | |
| SCHEMBL19900204 | 0.88 | NR1H4 (0.52) | NR1H4RETFABP1 | |
| SCHEMBL29386923 | 0.87 | NR1H4 (0.39) | NR1H4RETFABP1 | |
| SCHEMBL19899942 | 0.87 | NR1H4 (0.39) | NR1H4RETFABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116887827-A | Compounds and methods for modulating FXR | 拓臻制药公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2022147448-A1 | COMPOUNDS AND METHODS FOR MODULATING FXR | TERNS PHARMACEUTICALS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| CN-109265471-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-06-04 | — | — | CN | disclosed |
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |