Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15031277 | 0.75 | MAP3K5 (0.45) | MAP3K5MAPT | |
| SCHEMBL10254311 | 0.75 | KMT2A (0.49) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL24900930 | 0.72 | KMT2A (0.47) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL12483796 | 0.72 | NR4A2 (0.45) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL12167181 | 0.71 | KMT2A (0.56) | KMT2AMEN1LMNAPOLBKDM4E | |
| SCHEMBL30622587 | 0.71 | KMT2A (0.56) | KMT2AMEN1LMNAPOLBKDM4E | |
| SCHEMBL29715820 | 0.71 | MEN1 (0.49) | KMT2AMEN1LMNAPOLBNR4A2 | |
| SCHEMBL18911990 | 0.71 | MEN1 (0.46) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL2300491 | 0.71 | MAP3K5 (0.48) | KMT2AMEN1MAP3K5GABRPGABRD | |
| SCHEMBL19657567 | 0.71 | NR4A2 (0.52) | KMT2AMEN1MAP3K5MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |