Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31670249 | 1.00 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL8254856 | 1.00 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL22398001 | 1.00 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL2114177 | 1.00 | NR1H2 (0.53) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| Bicarbonate SCHEMBL30861201 | 0.94 | NR1H2 (0.48) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL19779324 | 0.91 | NR1H2 (0.50) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL21480200 | 0.91 | NR1H2 (0.50) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL19779325 | 0.91 | NR1H2 (0.50) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL19818365 | 0.89 | NR1H2 (0.46) | NR1H2USP2SMN1; SMN2RECQLCHRM2 | |
| SCHEMBL16080285 | 0.89 | NR1H2 (0.50) | NR1H2USP2SMN1; SMN2RECQLCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |