Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 17/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21840048 | 0.81 | NR1H4 (0.46) | NR1H4 | |
| SCHEMBL22790253 | 0.81 | NR1H4 (0.53) | NR1H4 | |
| SCHEMBL29618066 | 0.80 | NR1H4 (0.52) | NR1H4 | |
| SCHEMBL20031505 | 0.80 | NR1H4 (0.52) | NR1H4 | |
| SCHEMBL19202562 | 0.80 | NR1H4 (0.55) | NR1H4 | |
| SCHEMBL22790399 | 0.80 | NR1H4 (0.52) | NR1H4 | |
| SCHEMBL29904897 | 0.80 | NR1H4 (0.55) | NR1H4 | |
| SCHEMBL19202559 | 0.80 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL20944064 | 0.80 | NR1H4 (0.55) | NR1H4 | |
| SCHEMBL30436703 | 0.80 | NR1H4 (0.55) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |