Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 1/20 | 0.85 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.85 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.85 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.85 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.85 |
| ▸ | ATR | Q13535 | 2/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20032721 | 0.93 | DRD5 (0.73) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538918 | 0.93 | DRD5 (0.98) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL20348260 | 0.90 | DRD5 (0.78) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538902 | 0.89 | DRD5 (0.81) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538914 | 0.88 | DRD5 (0.90) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL20348262 | 0.88 | DRD5 (0.89) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL20348265 | 0.87 | DRD5 (0.69) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538924 | 0.86 | DRD5 (0.76) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538913 | 0.85 | DRD5 (0.85) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538919 | 0.84 | DRD5 (0.78) | DRD5SCNN1ASCNN1BSCNN1GHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938256-B2 | Annelated benzamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-04-10 | — | — | US | disclosed |