SCHEMBL20032727

SCHEMBL20032727

C=C(C)COc1cc(F)cc(-c2ccc(OCC3CC3C(C)=O)cc2)c1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17592798 0.93 FFAR4 (0.73) FFAR4
SCHEMBL19307496 0.93 FFAR4 (0.73) FFAR4
SCHEMBL17592527 0.91 FFAR4 (0.59) FFAR4
SCHEMBL19307363 0.91 FFAR4 (0.59) FFAR4
SCHEMBL20032756 0.85 FFAR4 (0.84) FFAR4
SCHEMBL20032762 0.84 FFAR4 (0.84) FFAR4
SCHEMBL20032729 0.84 FFAR4 (0.84) FFAR4
SCHEMBL19307550 0.77 FFAR4 (1.00) FFAR4
SCHEMBL19307547 0.77 FFAR4 (1.00) FFAR4
SCHEMBL19307401 0.75 FFAR4 (1.00) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938222-B2 Cyclopropanecarboxylic acid GPR120 modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2018-04-10 US disclosed