SCHEMBL20032770

SCHEMBL20032770

CC(=O)C1CC1CCc1ccc(-c2cccc(Oc3ccccc3)c2)cc1

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 0.83
FFAR1 O14842 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19307456 0.91 FFAR4 (1.00) FFAR4
SCHEMBL19307458 0.91 FFAR4 (1.00) FFAR4
SCHEMBL20032811 0.86 FFAR4 (0.83) FFAR4
SCHEMBL20032769 0.84 FFAR4 (0.85) FFAR4
SCHEMBL19307565 0.80 FFAR4 (1.00) FFAR4
SCHEMBL19307566 0.80 FFAR4 (1.00) FFAR4
SCHEMBL20032812 0.78 FFAR4 (0.81) FFAR4
SCHEMBL20032807 0.77 FFAR4 (0.81) FFAR4
SCHEMBL20032746 0.77 FFAR4 (0.83) FFAR4
SCHEMBL19307469 0.75 FFAR4 (1.00) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938222-B2 Cyclopropanecarboxylic acid GPR120 modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2018-04-10 US disclosed