SCHEMBL20032791

SCHEMBL20032791

COc1cc(-c2cc(Oc3cccc(F)c3)ccc2F)ccc1OCC1CC1C(C)=O

nearest known ligand 0.87

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17593071 0.93 FFAR4 (1.00) FFAR4
SCHEMBL19307412 0.93 FFAR4 (1.00) FFAR4
SCHEMBL20032789 0.92 FFAR4 (0.84) FFAR4
SCHEMBL20032751 0.88 FFAR4 (0.83) FFAR4
SCHEMBL20032723 0.85 FFAR4 (0.85) FFAR4
SCHEMBL19307407 0.83 FFAR4 (1.00) FFAR4
SCHEMBL19307408 0.83 FFAR4 (1.00) FFAR4
SCHEMBL20032794 0.83 FFAR4 (0.85) FFAR4
SCHEMBL20032725 0.81 FFAR4 (0.84) FFAR4
SCHEMBL20032737 0.80 FFAR4 (0.82) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938222-B2 Cyclopropanecarboxylic acid GPR120 modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2018-04-10 US disclosed