SCHEMBL20032792

SCHEMBL20032792

CC(=O)C1CC1COc1ccc(-c2cc(Oc3ccc(C)c(F)c3)ccc2F)cc1F

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20032798 0.93 FFAR4 (0.86) FFAR4
SCHEMBL19307561 0.92 FFAR4 (1.00) FFAR4
SCHEMBL19307562 0.92 FFAR4 (1.00) FFAR4
SCHEMBL20032723 0.90 FFAR4 (0.85) FFAR4
SCHEMBL20032801 0.89 FFAR4 (0.86) FFAR4
SCHEMBL20032789 0.88 FFAR4 (0.84) FFAR4
SCHEMBL20032757 0.85 FFAR4 (0.85) FFAR4
SCHEMBL19321756 0.85 FFAR4 (1.00) FFAR4
SCHEMBL20032790 0.83 FFAR4 (0.82) FFAR4
SCHEMBL19327004 0.82 FFAR4 (1.00) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938222-B2 Cyclopropanecarboxylic acid GPR120 modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2018-04-10 US disclosed