⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910457 | 0.80 | — | — | |
| SCHEMBL6911375 | 0.76 | — | — | |
| SCHEMBL13716616 | 0.75 | — | — | |
| SCHEMBL6911247 | 0.71 | — | — | |
| SCHEMBL17726110 | 0.70 | — | — | |
| SCHEMBL789284 | 0.67 | — | — | |
| SCHEMBL719037 | 0.67 | — | — | |
| SCHEMBL789232 | 0.67 | — | — | |
| SCHEMBL1659264 | 0.61 | — | — | |
| SCHEMBL8339439 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938258-B2 | Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof | Karyopharm Therapeutics Inc. (US) | 2018-04-10 | — | — | US | disclosed |