SCHEMBL20034061

SCHEMBL20034061

C=C[C@H](O)[C@@H](/C=C\Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RCE1 Q9Y256 1/20 0.43
MAOB P27338 1/20 0.40
HTT P42858 2/20 0.38
CA1 P00915 5/20 0.37
CA2 P00918 3/20 0.37
ARG2 P78540 1/20 0.37
SLC1A3 P43003 2/20 0.35
SLC1A2 P43004 2/20 0.35
SLC1A1 P43005 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
IDO1 P14902 1/20 0.34
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
AGXT P21549 1/20 0.33
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16308015 0.86 MAOB (0.44) RCE1MAOBHTTCA1CA2
SCHEMBL20034073 0.82 RCE1 (0.48) RCE1MAOBHTTCA1CA2
SCHEMBL20034083 0.79 RCE1 (0.43) RCE1HTTCA1CA2SLC1A3
SCHEMBL30999477 0.76 RCE1 (0.43) RCE1CA1CA2SLC1A3SLC1A2
SCHEMBL17679381 0.76 RCE1 (0.39) RCE1HTTCA1CA2SLC1A3
SCHEMBL13207904 0.76 RCE1 (0.39) RCE1HTTCA1CA2SLC1A3
SCHEMBL17679390 0.74 RCE1 (0.50) RCE1HTTSLC1A3SLC1A2SLC1A1
SCHEMBL24996979 0.73 SLC1A3 (0.41) RCE1CA1CA2SLC1A3SLC1A2
SCHEMBL18786509 0.73 RCE1 (0.44) RCE1HTTCA1CA2SLC1A3
SCHEMBL21440862 0.73 RCE1 (0.58) RCE1HTTCA1CA2SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938253-B2 Catalysts for efficient Z-selective metathesis TRUSTEES OF BOSTON COLLEGE (US) 2018-04-10 US disclosed