Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 14/20 | 0.61 |
| ▸ | HCK | P08631 | 11/20 | 0.61 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | SRC | P12931 | 4/20 | 0.51 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534207 | 0.88 | MAPK14 (0.75) | MAPK14MAPK12HCKTNFSRC | |
| SCHEMBL14701082 | 0.87 | MAPK14 (0.60) | MAPK14MAPK12HCKTNFSRC | |
| SCHEMBL19841213 | 0.86 | MAPK14 (0.68) | MAPK14MAPK12HCKTNFSRC | |
| SCHEMBL20036719 | 0.82 | MAPK14 (0.56) | MAPK14MAPK12HCKTNFSRC | |
| SCHEMBL20036744 | 0.81 | MAPK14 (0.69) | MAPK14MAPK12HCKSRCSYK | |
| SCHEMBL2532803 | 0.80 | MAPK14 (0.76) | MAPK14MAPK12HCKTNFSRC | |
| SCHEMBL19102004 | 0.80 | MAPK14 (0.61) | MAPK14MAPK12HCKSRCSYK | |
| SCHEMBL20060691 | 0.79 | MAPK14 (0.65) | MAPK14MAPK12HCKSRCSYK | |
| SCHEMBL20060621 | 0.79 | GSK3A (0.64) | MAPK14MAPK12HCKSRCSYK | |
| SCHEMBL12288114 | 0.79 | MAPK14 (0.75) | MAPK14MAPK12HCKSRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509595-B1 | INHIBITORS OF HEMOPOIETIC CELL KINASE (P59-HCK) AND THEIR USE IN THE TREATMENT OF INFLUENZA INFECTION | RESPIVERT LTD (GB) | 2018-04-11 | — | — | EP | disclosed |