Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291480 | 0.84 | PIM1 (0.44) | PIM1TLR8TLR7PIM3MAP4K1 | |
| SCHEMBL20255455 | 0.83 | PIM1 (0.41) | PIM1TLR8TLR7MAP4K1PRMT5 | |
| SCHEMBL20249425 | 0.82 | PIM1 (0.39) | PIM1TLR8TLR7PIM3PIM2 | |
| SCHEMBL1578400 | 0.81 | BPTF (0.43) | PIM1TLR8TLR7MAP4K1PRMT5 | |
| Hydrochloric Acid SCHEMBL1964613 | 0.80 | BPTF (0.42) | PIM1TLR8TLR7MAP4K1PRMT5 | |
| SCHEMBL255543 | 0.78 | SLC6A2 (0.43) | PIM1OPRM1OPRL1MAP4K1SLC6A2 | |
| SCHEMBL5767440 | 0.77 | PIM1 (0.44) | PIM1OPRM1OPRL1MAP4K1PRMT5 | |
| SCHEMBL18291201 | 0.77 | UHRF1 (0.36) | PIM1TLR8TLR7OPRM1OPRL1 | |
| SCHEMBL18291188 | 0.76 | TLR8 (0.38) | PIM1TLR8TLR7PIM3PIM2 | |
| SCHEMBL8306614 | 0.75 | SLC6A2 (0.40) | PIM1TLR8TLR7OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |