Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 3/20 | 0.40 |
| ▸ | CLK3 | P49761 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 11/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 11/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291289 | 0.82 | CLK2 (0.44) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL20038189 | 0.80 | CLK2 (0.40) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL20249298 | 0.79 | CLK2 (0.40) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL20249297 | 0.79 | CLK2 (0.40) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL18291287 | 0.78 | CLK2 (0.37) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL18291298 | 0.78 | CLK2 (0.37) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL18291595 | 0.78 | CLK2 (0.37) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL18291279 | 0.74 | SLC6A4 (0.37) | — | |
| SCHEMBL13171526 | 0.70 | CSF1R (0.41) | CLK2CLK3DYRK1APIM1PIM2 | |
| SCHEMBL13729306 | 0.69 | ACACB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |