Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291570 | 0.85 | HRH3 (0.39) | HRH3RXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20037471 | 0.85 | HRH3 (0.39) | HRH3RXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20037438 | 0.83 | HRH3 (0.45) | HRH3RXFP1TSHRMAPK1KMT2A | |
| SCHEMBL20037429 | 0.82 | HRH3 (0.44) | HRH3TSHRMAPK1KMT2AMEN1 | |
| SCHEMBL20037692 | 0.82 | HRH3 (0.44) | HRH3TSHRMAPK1KMT2AMEN1 | |
| SCHEMBL19302977 | 0.79 | TSHR (0.41) | HRH3RXFP1TSHRMAPK1KMT2A | |
| SCHEMBL12407039 | 0.78 | HRH3 (0.42) | HRH3RXFP1TSHRMAPK1KMT2A | |
| SCHEMBL12485053 | 0.78 | DPP4 (0.51) | HRH3RXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20249134 | 0.78 | HRH3 (0.42) | HRH3TSHRMAPK1KMT2AMEN1 | |
| SCHEMBL20249135 | 0.78 | HRH3 (0.42) | HRH3TSHRMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |