Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529241 | 0.74 | HTR2B (0.43) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL9529232 | 0.74 | HTR2B (0.43) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL9529220 | 0.74 | HTR2B (0.43) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL3578838 | 0.74 | MAPT (0.47) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL25659982 | 0.72 | MAPT (0.45) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL224104 | 0.71 | HIF1A (0.45) | MEN1MAPTKMT2AABCB1HTR1A | |
| Hydrochloric Acid SCHEMBL6596529 | 0.69 | CYP19A1 (0.45) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL10652491 | 0.68 | MAPT (0.42) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL619734 | 0.68 | MAPT (0.44) | KDM4EMEN1MAPTKMT2AABCB1 | |
| SCHEMBL31260267 | 0.68 | MAPT (0.47) | KDM4EMEN1MAPTKMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305794-A1 | SELECTIVE MODULATORS OF THE ACTIVITY OF THE GPR55 RECEPTOR: CHROMENOPYRAZOLE DERIVATIVES | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2018-04-11 | — | — | EP | disclosed |