SCHEMBL20040190

SCHEMBL20040190

Cc1ccc(C2(c3ccc(C)cc3)c3cc4c(cc3-c3cc5sc(-c6ccc(C=C(C#N)C#N)c7nsnc67)cc5cc32)C(c2ccc(C)cc2)(c2ccc(C)cc2)c2cc3cc(-c5ccc(C=C(C#N)C#N)c6nsnc56)sc3cc2-4)cc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 1/20 0.34
PABPC1 P11940 1/20 0.34
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
APP P05067 1/20 0.31
LMNA P02545 1/20 0.30
TNNI3 P19429 1/20 0.30
TNNT2 P45379 1/20 0.30
TNNC1 P63316 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20040162 0.96 MAPT (0.34) MAPTMEN1KMT2AKDM4EPABPC1
SCHEMBL20040195 0.95 MEN1 (0.32) MAPTMEN1KMT2AKDM4EPABPC1
SCHEMBL20040165 0.92 MEN1 (0.32) MAPTMEN1KMT2AKDM4EPABPC1
SCHEMBL20040166 0.91 MEN1 (0.32) MAPTMEN1KMT2AKDM4EPABPC1
SCHEMBL20042503 0.91 MEN1 (0.32) MAPTMEN1KMT2AKDM4EPABPC1
SCHEMBL20042502 0.89 KDM4E (0.31) MAPTMEN1KMT2AKDM4EPABPC1
SCHEMBL20040211 0.88
SCHEMBL20040180 0.88
SCHEMBL20042501 0.87 MEN1 (0.32) MAPTMEN1KMT2AKDM4EPABPC1
SCHEMBL20040197 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3306690-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2022-09-07 EP disclosed
US-10411190-B2 Organic semiconducting compounds MERCK PATENT GMBH (DE) 2019-09-10 US disclosed
EP-3306690-A1 ORGANIC SEMICONDUCTING COMPOUNDS Merck Patent GmbH (DE) 2018-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10411190-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC MAPT 45/4885MEN1 2981/4885KMT2A 1170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.