Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14870489 | 1.00 | HSD17B10 (0.38) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL4302765 | 0.84 | CHRM2 (0.41) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL30516973 | 0.84 | CHRM2 (0.41) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL21554858 | 0.82 | NR1H2 (0.44) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL497157 | 0.82 | NR1H2 (0.46) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL15184282 | 0.82 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL15184287 | 0.82 | NR1H2 (0.46) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL6346470 | 0.82 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL15247679 | 0.82 | PREP (0.38) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL2328258 | 0.82 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2811997-B1 | SUBSTITUTED PROLINES/PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS | EOLAS THERAPEUTICS INC (US) | 2018-04-11 | — | — | EP | disclosed |