SCHEMBL2004041

SCHEMBL2004041

CO[Si](CCCS)(CCCOCC1CO1)OC

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337022 0.92 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17373043 0.90 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1618416 0.88 TSHR (0.52) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL11767225 0.86 SMN1; SMN2 (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL14840164 0.86 SMN1; SMN2 (0.66) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28281868 0.84 TSHR (0.52) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL230071 0.84 SMN1; SMN2 (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4800731 0.83 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10015848 0.83 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL20240416 0.82 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304025-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20110217452-A1 OPTICAL FILM, POLARIZING PLATE, IMAGE DISPLAY, AND MANUFACTURING METHOD OF OPTICAL FILM FUJIFILM CORPORATION (JP) 2011-09-08 US disclosed
US-7960018-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2011-06-14 US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed