Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.84 |
| ▸ | BRAF | P15056 | 15/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16907492 | 0.92 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907497 | 0.85 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907524 | 0.84 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907661 | 0.82 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907480 | 0.82 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907390 | 0.82 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907592 | 0.81 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907468 | 0.81 | KDR (1.00) | KDRBRAF | |
| SCHEMBL30729916 | 0.78 | KDR (0.70) | KDRBRAF | |
| SCHEMBL15541508 | 0.78 | KDR (0.70) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |