Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.86 |
| ▸ | BRAF | P15056 | 6/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16904593 | 0.93 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16904578 | 0.86 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16904590 | 0.83 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16904589 | 0.83 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907444 | 0.82 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907509 | 0.82 | KDR (1.00) | KDRBRAF | |
| SCHEMBL20040907 | 0.81 | KDR (0.90) | KDRBRAF | |
| SCHEMBL16907541 | 0.79 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16907547 | 0.79 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16904594 | 0.78 | KDR (1.00) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |