SCHEMBL20041092

SCHEMBL20041092

CCC(C)C(=O)N1CCC(NC(=O)Nc2ccc(C(=O)C(F)(F)F)cc2)CC1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15155469 0.88 EPHX2 (1.00) EPHX2
SCHEMBL2730089 0.88 EPHX2 (1.00) EPHX2
SCHEMBL15155663 0.85 EPHX2 (1.00) EPHX2
SCHEMBL16368742 0.85 EPHX2 (0.81) EPHX2
SCHEMBL14997500 0.85 EPHX2 (0.81) EPHX2
SCHEMBL15155343 0.84 EPHX2 (1.00) EPHX2
SCHEMBL15155923 0.84 EPHX2 (1.00) EPHX2
SCHEMBL15155510 0.84 EPHX2 (1.00) EPHX2
SCHEMBL30901142 0.83 EPHX2 (0.75) EPHX2
SCHEMBL28428116 0.83 EPHX2 (0.75) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2809650-B1 ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE UNIV CALIFORNIA (US) 2018-04-11 EP disclosed