Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 0.72 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18307140 | 0.89 | EPHX1 (0.84) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23406296 | 0.85 | EPHX1 (0.90) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2752957 | 0.85 | EPHX1 (0.97) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14997509 | 0.84 | EPHX1 (0.72) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11927282 | 0.84 | EPHX1 (0.63) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16825746 | 0.84 | EPHX1 (0.72) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1425082 | 0.84 | EPHX1 (0.72) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12995588 | 0.84 | EPHX1 (0.63) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4319424 | 0.84 | EPHX1 (1.00) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6621016 | 0.84 | EPHX1 (0.71) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809650-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2018-04-11 | — | — | EP | disclosed |