SCHEMBL20041203

SCHEMBL20041203

CN1CCCC1(C)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.42
KMT2A Q03164 1/20 0.37
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 3/20 0.34
TSHR P16473 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
BLM P54132 1/20 0.34
CACNA2D1 P54289 1/20 0.34
KDM1A O60341 1/20 0.33
NFKB1 P19838 1/20 0.32
MAPK1 P28482 1/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25349940 0.77 FFAR1 (0.38) FFAR1KMT2ACYP2C19CYP1A2TSHR
SCHEMBL24718527 0.74
SCHEMBL13448668 0.74
SCHEMBL25349071 0.74
Iodide SCHEMBL28867004 0.72 EHMT2 (0.32)
SCHEMBL5585735 0.72
SCHEMBL15426524 0.72
SCHEMBL6658044 0.70
SCHEMBL12546726 0.69
SCHEMBL12547112 0.69 CYP4F2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093355-B Preparation method of pyrrole ester compound 河南农业大学 2024-06-04 CN disclosed
CN-116239822-A Preparation method of polymer flame retardant 合肥安邦化工有限公司 2023-06-09 CN disclosed
EP-3140297-B1 PYRROLIDINE GPR40 MODULATORS FOR THE TREATMENT OF DISEASES SUCH AS DIABETES BRISTOL MYERS SQUIBB CO (US) 2018-04-11 EP disclosed